Jeffrey Loeb

Jeffrey Loeb on west campus. Photo: Jenny Fontaine/UIC

Dr. Jeffrey Loeb is the John S. Garvin Endowed Chair in neurology and professor and head of the UIC Department of Neurology and Rehabilitation in the College of Medicine.

As a clinician, Loeb leads the UI Health neurology service and specializes in the evaluation and treatment of epilepsy. He is an expert in the medical and surgical management of patients with hard-to-control seizures, including rare disease populations such as Sturge-Weber Syndrome.

He has pioneered a unique systems-biology approach and directs the UI NeuroRepository to diagnose and treat brain diseases through multimodal data integration of clinical and research data types in novel AI-ready databases. These data are linked to precisely mapped human brain and spinal cord tissues, where he looks not only at the cellular composition, but every gene, protein and molecule. Loeb has developed a deeper understanding and advanced new therapeutics for diseases ranging from epilepsy, Sturge-Weber Syndrome, ALS and Alzheimer’s disease. His work has led to patented drugs and technologies that he is actively working toward commercialization.